Principal Scientist, Model-Based Meta-Analysis

Company: Disability Solutions
Location: San Diego
Posted on: September 25, 2024

Job Description:

Johnson & Johnson is currently seeking a Principal Scientist, Model-Based Meta-Analysis (MBMA). This position can be located in San Diego, CA; Titusville, NJ; Raritan, NJ; or Spring House, PA. Additional Johnson & Johnson Innovative Medicine sites within the United States may be considered.\rAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com.\rFor more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.\rWe know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.\rAt Johnson & Johnson, we all belong.\rThe Quantitative Sciences and Clinical Pharmacology (QSCP) group at Janssen uses mathematical modeling techniques to integrate data from various sources to facilitate model-informed decisions for drug development. The Model-Based Meta-Analysis (MBMA) group provides the quantitative expertise in building integrative models from published clinical trials to facilitate benchmarking, Go/No-go decisions and staged clinical trial design. The group works with clinical development teams across various therapeutic areas to find opportunities to apply such integrative models in informed decision making. This individual will report to the Head of the MBMA group.\rPrincipal Responsibilities:

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• Develop MBMA models based on internal and external aggregate-level data.
• Support clinical development teams through utilization of MBMA models to improve clinical trial design and decision making.
• Effectively communicate results through presentations and summarize methods and results through reports and other documents.
• Work collaboratively across various functions to support the identification of new opportunities for data-informed decision making at program and portfolio levels. Additionally, support initiatives to collaborate with other quantitative groups to create value in the Janssen pipeline and contribute to Janssen as a leader in model-informed drug discovery and development.
• External collaborations, visibility, and impact: support in engaging in external collaborations within professional associations (e.g., International Society of Pharmacovigilance (ISoP)), presenting at scientific meetings, and publishing in peer reviewed journals to influence the external pharmaceutical industry and regulatory environment.
• Carry out functional responsibilities in accordance with applicable SOPs/Guidelines and Regulatory requirements.
• Assist in process improvement initiatives and SOP/Guideline development.
• Work closely with Clinical Development Leads (CDLs) and other Clinical Development Team (CDT) members as well as members within Clinical Pharmacology and Pharmacometrics and Statistical and Decision Sciences. Will also work with external vendors as needed.\r\r

Keywords: Disability Solutions, National City , Principal Scientist, Model-Based Meta-Analysis, Other , San Diego, California